8.1 Acquisition of Ra Pharmaceuticals Inc.

On October 10, 2019, UCB announced that it had reached an agreement whereby UCB would purchase and acquire 100% of the outstanding shares of Ra Pharmaceuticals Inc., a U.S. clinical-stage biopharma company based in Cambridge, Massachusetts.

8.2 Acquisition of Engage Therapeutics Inc.

On June 5, 2020, UCB acquired Engage Therapeutics Inc.